HIPPIE v3.0 is online with new data, high-confidence negatives, machine learning-ready splits, and a new look. Check it out at https://hippie-db.net/! HIPPIE now contains ~1.2 million experimentally supported PPIs, including…
Towards reconstruction of the human interactome from positive and negative experimental evidence is now available at bioRxiv at https://doi.org/10.64898/2026.09.09.750397. We introduce a method to derive high-confidence interacting and, more importantly,…
Are You Learning Biological Signal or Shortcuts? Auditing and Mitigating Bias in Protein-Protein Interaction Datasets is now available at arXiv at https://doi.org/10.48550/arXiv.2609.10193. We systematically characterize both reported and, to our…
Konstantin Pelz has begun his four-month research exchange in Milan, joining the group of Martin Schäfer. This visit will allow him to collaborate more closely with the WP1 team, including…
Judith Bernett joins CoBiNet as a new scientific researcher at the FAU. She continues Nicolai Meyerhöfer’s work on WP2 (context-specific PPIs). Before, she was a PhD candidate in Prof. Markus…
The second annual CoBiNet meeting was held at the IEO in Milan (Italy) from October 9-10, 2025. Teams presented progress on the curation of non-interactions (WP1), tissue-specific interactions (WP2), and…
Inference of differential kinase interaction networks with KINference is published in Bioinformatics (https://doi.org/10.1093/bioinformatics/btaf349). KINference combines computation of a baseline kinase interaction network (KIN) representing the space of all possible kinase–substrate…
DIGGER 2.0: digging into the functional impact of differential splicing on human and mouse disorders is published in Nucleic Acids Research (https://doi.org/10.1093/nar/gkaf384). DIGGER 2.0 now features both experimental and newly…
Konstantin P. met there with Prof. Christoph Dietrich and Dr. Enio Gjerga from University Hospital Heidelberg (UKHD) to foster synergies within CoBiNet project enabled by the Klaus Tschira Stiftung. Together,…
Joel Ås joins CoBiNet as a new scientific researcher at the IEO Milan. He continues the work on WP1 (curation of non-interactions). He obtained his PhD from the Uppsala University…
